Anatoliy I Masyuk Selected Research

Cysts

1/2022	Polycystic Liver Disease: Advances in Understanding and Treatment.
1/2022	Autophagy promotes hepatic cystogenesis in polycystic liver disease by depletion of cholangiocyte ciliogenic proteins.
1/2018	Cholangiocyte autophagy contributes to hepatic cystogenesis in polycystic liver disease and represents a potential therapeutic target.
10/2017	TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases through cyclic adenosine monophosphate/Gαs signaling.
1/2017	Therapeutic Targets in Polycystic Liver Disease.
1/2015	TGR5 in the Cholangiociliopathies.
3/2014	HDAC6 is overexpressed in cystic cholangiocytes and its inhibition reduces cystogenesis.
7/2013	Pasireotide is more effective than octreotide in reducing hepatorenal cystogenesis in rodents with polycystic kidney and liver diseases.
3/2012	Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease.
1/2009	The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD).

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Anatoliy I Masyuk Research Topics

Disease

13	Cysts 01/2022 - 11/2003
12	Polycystic liver disease 01/2022 - 03/2007
8	Autosomal Recessive Polycystic Kidney (Polycystic Kidney Disease, Infantile, Type I) 01/2022 - 03/2007
8	Liver Diseases (Liver Disease) 10/2017 - 03/2007
7	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2018 - 11/2003
4	Disease Progression 01/2018 - 03/2007
3	Inborn Genetic Diseases (Disease, Hereditary) 01/2022 - 01/2017
2	Autosomal Dominant Polycystic Kidney (ADPKD) 01/2017 - 07/2013
2	Fibrosis (Cirrhosis) 03/2014 - 03/2007
1	Cholangiocarcinoma 01/2015
1	Sclerosing Cholangitis 01/2015
1	Bardet-Biedl Syndrome (Syndrome, Bardet-Biedl) 02/2009
1	Gallstones (Gallstone) 10/2008
1	Hyperplasia 10/2008

Drug/Important Bio-Agent (IBA)

8	1-dodecylpyridoxal (PLD)IBA 01/2022 - 03/2012
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2003
4	Somatostatin Receptors (Somatostatin Receptor)IBA 01/2018 - 03/2007
3	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2017 - 03/2007
3	CalciumIBA 01/2017 - 01/2009
2	Small Interfering RNA (siRNA)IBA 01/2018 - 10/2017
2	Pharmaceutical PreparationsIBA 01/2018 - 01/2017
2	Adenosine Monophosphate (AMP)IBA 10/2017 - 01/2009
2	pasireotideIBA 10/2017 - 07/2013
2	Octreotide (Sandostatin)FDA LinkGeneric 07/2013 - 03/2007
2	Bile Acids and Salts (Bile Acids)IBA 06/2013 - 10/2008
2	Adenosine (Adenocard)FDA LinkGeneric 01/2009 - 03/2007
1	bafilomycin A1IBA 01/2018
1	Histone Deacetylase 6IBA 01/2018
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2018
1	Oleanolic AcidIBA 10/2017
1	pyrimidineIBA 10/2017
1	m-tolyl 5- chloro- 2- (ethylsulfonyl)pyrimidine- 4- carboxylateIBA 10/2017
1	Taurolithocholic AcidIBA 10/2017
1	Transient Receptor Potential ChannelsIBA 01/2017
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2017
1	Sirolimus (Rapamycin)FDA Link 01/2017
1	cdc25 PhosphatasesIBA 01/2017
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2017
1	MicroRNAs (MicroRNA)IBA 01/2017
1	Metalloproteases (Metalloproteinases)IBA 01/2017
1	LigandsIBA 01/2015
1	tubacinIBA 03/2014
1	ricolinostatIBA 03/2014
1	tubastatin AIBA 03/2014
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 03/2012
1	Vitamin K 3 (Menadione)FDA Link 03/2012
1	Cell Cycle ProteinsIBA 03/2012
1	polycystic kidney disease 1 proteinIBA 02/2009
1	polycystic kidney disease 2 proteinIBA 02/2009
1	ADP-Ribosylation Factors (ADP-Ribosylation Factor)IBA 02/2009
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2009
1	erythromycin propionate-N-acetylcysteinateIBA 01/2009
1	Aquaporins (Water Channels)IBA 12/2008
1	AcidsIBA 12/2008
1	Benzoic Acid (Potassium Benzoate)FDA Link 12/2008
1	SaltsIBA 12/2008
1	Secretin FDA Link 12/2008
1	CholesterolIBA 10/2008

Therapy/Procedure

2	Therapeutics 09/2013 - 03/2012
1	Aftercare (After-Treatment) 10/2017